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Epigenetic Leverage

NCBI Epigenomic Data Sets

Impact of nutritional epigenomics on disease risk and prevention: introduction.

Foodomics: a new comprehensive approach to food and nutrition.

Epigenetic effects of environmental chemicals bisphenol a and phthalates. Singh S, Li SS. Int J Mol Sci. 2012;13(8):10143-53. Epub 2012 Aug 15.

Fetal origins of adult disease.

More than just a pretty face. The relationship between infant’s temperament, food acceptance, andmothers‘ perceptions of their enjoyment of food.

Effect of maternal diet on the epigenome: implications for human metabolic disease.

Maternal dietary patterns and associated nutrient intakes during each trimester of pregnancy. McGowan CA, McAuliffe FM. Public Health Nutr. 2012 Apr 12:1-11. [Epub ahead of print]

Epigenetics and maternal nutrition: nature v. nurture.

Epigenetic programming by maternal nutrition: shaping future generations.  Li CC, Maloney CA, Cropley JE, Suter CM. Epigenomics. 2010 Aug;2(4):539-49. Review.

Periconceptional nutrition and the early programming of a life of obesity or adversity.

Evidence for the relationship between diet and cancer.

Targeting the epigenome with bioactive food components for cancer prevention.

Epigenetic impact of dietary polyphenols in cancer chemoprevention: lifelong remodeling of our epigenomes.

How epigenomics brings phenotype into being.

Epigenetics in autism and other neurodevelopmental diseases.

Effects of micronutrients on DNA repair.

Nutritional factors in mental health: does ‘epigenetics’ provide a road map?

Recent advances in nutrition, genes and brain health.

Prenatal nutrition, epigenetics and schizophrenia risk: can we test causal effects?

Why are genetics important for nutrition? Lessons from epigenetic research.

Environmental Stress Affects DNA Methylation of a CpG Rich Promoter Region of Serotonin Transporter Gene in a Nurse Cohort

Biomarkers of nutrient bioactivity and efficacy: a route toward personalized nutrition.

The coming of age of nutrigenetics and nutrigenomics.

Online tools for bioinformatics analyses in nutrition sciences.

Homeostatic Imbalance and Colon Cancer: The Dynamic Epigenetic Interplay of Inflammation, Environmental Toxins, and Chemopreventive Plant Compounds

Nutritional status affects the epigenomic profile of peripheral blood cells.

Nutritional influences on epigenetics and age-related disease.

Genetic profiling in inflammatory bowel disease: from association to bedside.

Nutrigenomics: where are we with genetic and epigenetic markers for disposition and susceptibility?

Effects of arsenic exposure on DNA methylation and epigenetic gene regulation.  Reichard JF, Puga A. Epigenomics. 2010 Feb;2(1):87-104. Review.

Epigenetics in women’s health care. Pozharny Y, Lambertini L, Clunie G, Ferrara L, Lee MJ.  Mt Sinai J Med. 2010 Mar-Apr;77(2):225-35. Review.

Class 1 Epigenomes

  • DNA methylation (whole genome bisulfite sequencing)
  • “core” histone modifications and an expanded set of histone modifications
  • RNA sequencing data (RNA-seq)
  • Chromatin accessibility

Class 2 Epigenomes

  • DNA methylation (whole genome bisulfite sequencing)
  • “core” histone modifications
  • RNA sequencing data (RNA-seq)
  • Chromatin accessibility (if possible)

Class 3 Epigenomes

  • DNA methylation (RRBS, MeDIP-seq, MRE-seq)
  • “core” histone modifications
  • RNA sequencing data (gene expression microarray)
  • Chromatin accessibility (if possible)

Class 4 Epigenomes

  • DNA methylation (RRBS, MeDIP-seq, MRE-seq)
  • “core” histone modifications
  • RNA sequencing data (gene expression microarray)
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